Beilstein J. Org. Chem.2016,12, 1453–1458, doi:10.3762/bjoc.12.141
Golo Storch Sebastian Pallmann Frank Rominger Oliver Trapp Organisch-Chemisches Institut, Ruprecht-Karls Universität Heidelberg, Im Neuenheimer Feld 270, 69120 Heidelberg, Germany 10.3762/bjoc.12.141 Abstract Stereodynamicligands offer intriguing possibilities in enantioselective catalysis. “NU
preparation of tailor-made functionalized stereodynamicligands possible and give an outline for possible applications in enantioselective catalysis.
Keywords: atropisomer; enantioselective DHPLC; ligand design; non-covalent interactions; Okamoto phases; phosphine ligand; stereodynamicligands; Introduction
][6], palladium [7][8], platinum [9][10] and gold [11][12][13] in combination with chiral co-ligands or counter ions that are used after alignment of the ligand’s axial chirality.
One major advantage of stereodynamicligands is that there is no need for separate preparation of one ligand enantiomer as
PDF
Graphical Abstract
Figure 1:
Synthetic overview of “NU-BIPHEP(O)s”. A) Rhodium catalyzed double [2 + 2 + 2] cycloaddition. B) Ac...